The Effects of Total Thyroidectomy on Cardiac Function in Old Rats using Echocardiographic Measures

نویسندگان

  • Julio Cesar Francisco
  • Ricardo Correa Cunha
  • Marco André Cardoso
  • Rossana Baggio Simeoni
  • Luiz Cesar Guarita-Souza
  • Nelson Itiro Miyague
چکیده

Methods: Female Wistar rats aged 24 months old (referred to as adult) were divided into 2 groups with 15 animals each: Euthyroid (Eut) and Hypothyroid (Hypo) rats. Hypothyroidism was induced by total thyroidectomy. The plasmatic levels of T3, T4, TSH and free ionic calcium were measured. Echocardiographic analysis was performed using the following parameters: left ventricular end-diastolic (LVED) left ventricular end-systolic (LVES), ejection fraction (EF) and Tei index.

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تاریخ انتشار 2013